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Project: Cellular-Level Pilot
Description: Extends the original COXEN method to select genes that are predictive of the efficacies of multiple drugs for building general drug response prediction models that are not specific to a particular drug.
DESCRIPTION:

Extends the original COXEN method to select genes that are predictive of the efficacies of multiple drugs for building general drug response prediction models that are not specific to a particular drug.

IMPACT: Enables building of anti-cancer drug response prediction models using selected genes and drugs.
PRIMARY PUBLICATION: Enhanced Co-Expression Extrapolation (COXEN) Gene Selection Method for Building Anti-Cancer Drug Response Prediction Models
INPUT DATA TYPE: RNA-Seq, Drug Molecular Descriptors
INPUT DATA FORMAT: Tabular
LEVEL OF DOCUMENTATION: Minimal
AVAILABLE ON GITHUB
https://github.com/CBIIT/NCI-DOE-Collab-Pilot1-Enhanced_COXEN
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